graphjnr.blogg.se

Methanol antidote
Methanol antidote













methanol antidote

Hemodialysis accelerates the elimination of both methanol and formic acid and also assists in correction of the metabolic acidosis.

methanol antidote

Specific therapeutic measures include correction of the metabolic acidosis with sodium bicarbonate and administration of enteral or parenteral ethanol to competitively inhibit the metabolic breakdown of methanol to formic acid. The presence of metabolic acidosis associated with an increased anion gap and increased osmol gap are important laboratory findings. Because antidotal treatment is available it is important to recognize methanol poisoning promptly. The diagnosis is sometimes elusive and requires a high index of suspicion.

methanol antidote

While methanol itself may be harmless, it is converted in vivo to the highly toxic formic acid. Methanol ingestion is an uncommon form of poisoning that can cause severe metabolic disturbances, blindness, permanent neurologic dysfunction and death.















Methanol antidote